赵润州,倪铭,法云智,伯晓晨*,焦剑*.华盛顿大学蛋白质设计研究所创新之道及其对生命科学新型研发机构建设的启示[J].中国科学院院刊,2024,39(7):1235-1244.

华盛顿大学蛋白质设计研究所创新之道及其对生命科学新型研发机构建设的启示

Innovation path at Institute for Protein Design of Washington University and its enlightenment for construction of new life sciences R&D institutions
作者
赵润州
军事科学院军事医学研究院 北京 100850
ZHAO Runzhou
Academy of Military Medical Sciences, Academy of Military Sciences, Beijing 100850, China
倪铭
军事科学院军事医学研究院 北京 100850
NI Ming
Academy of Military Medical Sciences, Academy of Military Sciences, Beijing 100850, China
法云智
军事科学院军事医学研究院 北京 100850
FA Yunzhi
Academy of Military Medical Sciences, Academy of Military Sciences, Beijing 100850, China
伯晓晨*
军事科学院军事医学研究院 北京 100850
BO Xiaochen*
Academy of Military Medical Sciences, Academy of Military Sciences, Beijing 100850, China
焦剑*
军事科学院军事医学研究院 北京 100850
JIAO Jian*
Academy of Military Medical Sciences, Academy of Military Sciences, Beijing 100850, China
中文关键词
         蛋白质设计;新型研发机构;生命科学;科技创新
英文关键词
        protein design;new R&D institutions;life sciences;scientific and technical innovation
中文摘要
        蛋白质设计研究所是美国华盛顿大学发起,州政府、联邦政府等支持的非营利性科研机构。自2012年成立起,该研究所抢抓人工智能驱动科学研究(AI for Science)、开放科学发展机遇,提升原始创新、技术供给和产品生成能力,现已成为全球生命科学前沿创新的关键力量。研究表明,其成功得益于深耕基础前沿先做强再做大、人工智能赋能干湿结合领跑新范式、推动创新链与产业链融合发展、发挥战略科学家定向引航作用、构建开放共享融合创新生态。借鉴其经验,中国可发挥新型举国体制优势,从聚焦顶层设计加强制度保障、立足以精立业抢占变革先机、突出市场导向集聚创新要素、坚持以人为本营造宽松环境等方面,更好地推动生命科学新型研发机构高质量发展,支撑生命科学高水平自立自强。
英文摘要
        The Institute for Protein Design (IPD) at the University of Washington is a pioneering local and state-supported non-profit scientific research institution. Since its establishment in 2012, IPD has seized the opportunity of AI for Science and open science, and continuously enhanced its capabilities of fundamental innovations, breakthrough technologies, and industrial impact. We summarized five factors contributing to IPD’s development, including focusing on the cutting-edge issues of basic scientific research to gain a firstmover advantage and then further expand, integrating AI-enhanced digital tools and solid experimental validations, facilitating the integrated development of innovation and industrial chains, giving full play to the role of strategic scientists, and creating an open and sharing atmosphere for talents. While drawing on its experience, we suggest that China can make use of the new national system to enhance the development of new life sciences R&D institutions in four aspects: strengthening top-level design and institutional frameworks, seizing the opportunities of technological transformation, highlighting market-oriented convergence of innovation elements, and adhering to a people-oriented and lenient environment, in order to support life sciences self-reliance and selfstrengthening at higher levels.
DOI10.16418/j.issn.1000-3045.20240228007
作者简介
赵润州 军事科学院军事医学研究院助理研究员。主要研究领域:科研管理、科技评估。
E-mail:kiddjojo@163.com
伯晓晨 军事科学院军事医学研究院研究员。主要研究领域:生物医学人工智能技术。
E-mail:boxiaoc@163.com
焦剑 军事科学院军事医学研究院研究员。主要研究领域:生物安全与国防生物科技战略论证。
E-mail:jiaojian168@sina.com
ZHAO Runzhou Assistant Professor of Academy of Military Medical Sciences, Academy of Military Sciences. His research focuses on scientific research management, science & technology assessment.
E-mail: kiddjojo@163.com
BO Xiaochen Professor of Academy of Military Medical Sciences, Academy of Military Sciences. His research focuses on biomedical artificial intelligence technology.
E-mail: boxiaoc@163.com
JIAO Jian Professor of Academy of Military Medical Sciences, Academy of Military Sciences. His research focuses on biodefense and defense biotechnology strategic study.
E-mail: jiaojian168@sina.com
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