李鑫,于汉超.人工智能驱动的生命科学研究新范式[J].中国科学院院刊,2024,39(1):50-58.

人工智能驱动的生命科学研究新范式

A new paradigm of life science research driven by artificial intelligence

李鑫^1,2
中国科学院动物研究所 北京 100101;北京干细胞与再生医学研究院 北京 100101
LI Xin^1,2
Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China;Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China
于汉超^3*
中国科学院 前沿科学与教育局 北京 100864
YU Hanchao^3*
Bureau of Frontier Sciences and Education, Chinese Academy of Sciences, Beijing 100864, China

         科学研究;生命科学;人工智能;大数据;科学范式

        scientific research;life science;artificial intelligence;big data;scientific paradigm

        生物技术和信息技术的迅速发展，使生命科学进入了数据爆发的新时代，传统生命科学研究范式难以在日益增长的生物大数据中揭示生命复杂系统的本质规律。随着人工智能（AI）在生命科学研究领域持续取得颠覆性突破，AI驱动的生命科学研究新范式呼之欲出。文章通过深入剖析AI驱动的生命科学研究的典型范例，提出了生命科学研究新范式的内涵和关键要素，阐述并讨论了新范式下的生命科学研究前沿和我国面临的挑战。

        The rapid development of biotechnology and information technology has brought life sciences into a new era of data explosion. The traditional life science research paradigm struggles to reveal the fundamental rules of complex biological systems from rapidly growing biological big data. As artificial intelligence continues to achieve disruptive breakthroughs in life science, a new paradigm driven by AI is emerging. This study delves into typical examples of life science research driven by AI, proposes the concept and key elements of the new life science research paradigm, elaborates on the cutting-edge of life science research under this new paradigm, and discusses the challenges in China.