细胞治疗药物：进展与展望

Cell-based medicinal products: Progress and perspectives

        惠利健*(中国科学院分子细胞科学卓越创新中心 200031)
        袁湘(中国科学院分子细胞科学卓越创新中心 200031)
        吴婧琪(中国科学院分子细胞科学卓越创新中心 200031)

         细胞药物;细胞制备;细胞治疗

        Cell-based medicinal products;cell manufacture;cell therapy

        近年来，细胞作为一种新型药物，在疾病治疗中取得了巨大进展，尤其在多种难治性疾病治疗中获得了前所未有的成功，迅速成为全球的研究热点。文章介绍了细胞治疗的概念及其发展现状；根据细胞治疗药物的分类，系统总结了不同类型细胞作为药物在相应疾病治疗中的研究亮点；最后，对我国细胞治疗领域的整体发展趋势进行展望，特别关注了在基础研究、细胞药物化、工艺研发，以及政策层面如何进一步推动细胞药物的临床转化应用和产业化。

        Cell-based medicinal products are a breakthrough that has been proven to treat previously incurable diseases, making them a topic of global interest. This review delves into the current state and progress of cell therapy, highlighting the remarkable therapeutic effects of various types of cell-based medicinal products. We specifically explore the potential development of cell-based medicinal products in China, focusing on promoting clinical translation and commercialization. We propose necessary actions to achieve these goals, such as fostering cutting-edge basic research, innovative therapeutic approaches, scalable manufacturing processes, and policy changes.