从基础研究走向实际应用的探索与思考——以中国科学院病原微生物与免疫学重点实验室为例

Thoughts on Basic Research to Practical Application: Case Study on CAS Key Laboratory of Pathogenic Microbiology and Immunology
作者
        施一(中国科学院微生物研究所 北京 100101)
中文关键词
         基础研究;实际应用;科技创新;创新文化
英文关键词
        basic research;practical application;science and technology innovation;innovation culture
中文摘要
        加强基础研究是实现高水平科技自立自强的核心举措之一。建党百年之际,回顾新中国科技事业发展历程,总结利于促进科技事业发展、推动基础研究走向实际应用的经验,并指出中国科学院开启的创新文化建设是创造有利于基础研究环境的重要举措。文章进一步陈述了中国科学院病原微生物与免疫学重点实验室从基础研究走向实际应用的探索和实践经验。
英文摘要
        Strengthening basic research is one of the key strategies to achieve high-quality self-reliance of science and technology. On the occasion of the Centenary of the Communist Party of China, we review the development of science and technology in China and summarize the experience of promoting basic research to practical application. We also point out that the construction of innovation culture initiated by Chinese Academy of Sciences is useful to create a favorable environment for the basic research. Moreover, we describe the experience of how CAS Key Laboratory of Pathogenic Microbiology and Immunology promotes basic research to practical application.
DOI10.16418/j.issn.1000-3045.20210605002
作者简介
施一 中国科学院微生物研究所研究员,中国科学院病原微生物与免疫学重点实验室副主任。中国青年科技工作者协会生物与医药科学专业委员会秘书长,中国科学院青年创新促进会第五届理事会理事长。长期从事病原感染调控的分子机制、免疫细胞受体与配体相互作用与识别机制研究,以及药物研发。对流感病毒、埃博拉病毒、寨卡病毒、沙粒病毒、冠状病毒等的感染过程进行了深入研究,取得一系列重要进展。曾担任国家传染病科技重大专项项目首席科学家,主持国家自然科学基金优秀青年基金、面上项目,以及中国科学院战略性先导科技专项项目、中国科学院青年创新促进会优秀会员项目等。发表SCI论文100余篇,其中以第一或通信作者在Cell、Nature、Science等期刊发表20余篇。
E-mail:shiyi@im.ac.cn
SHI Yi Principal Investigator and Professor at Institute of Microbiology,Chinese Academy of Sciences (CAS).Deputy Director for CAS Key Laboratory of Pathogenic Microbiology and Immunology (CASPMI).He is also the Secretary General of the Biological and Medical Sciences Committee of the Chinese Association of Young Scientists and Technologists,Fifth Director General of Youth Innovation Promotion Association of CAS.Dr.Shi mainly focuses on the molecular mechanism of pathogen infection and regulation by the host,and the interaction between receptors and ligands during immune response.He has been supported by the National Science and Technology Major Project (as Chief Scientist),the Excellent Young Scientists Fund of National Natural Science Foundation of China,the Strategic Priority Research Program of CAS,and Youth Innovation Promotion Association of CAS (excellent member).He has made remarkable contributions on the infection mechanism of several important human pathogens including influenza virus,Ebola virus,ZIKV,arenavirus,and coronaviruses.More than 100 SCI indexed papers have been published in international academic journals,including more than 20 of them,as first or corresponding authors (including co-first or corresponding),published in Cell,Nature,Science,etc.
E-mail:shiyi@im.ac.cn
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